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Induction of indoleamine 2,3‐dioxygenase by Borrelia burgdorferi in human immune cells correlates with pathogenic potential
Author(s) -
Love Andrea C.,
Schwartz Ira,
Petzke Mary M.
Publication year - 2015
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.4a0714-339r
Subject(s) - borrelia burgdorferi , biology , indoleamine 2,3 dioxygenase , microbiology and biotechnology , c c chemokine receptor type 7 , immune system , tlr7 , immunology , kynurenine , virology , chemokine , toll like receptor , innate immune system , antibody , genetics , chemokine receptor , amino acid , tryptophan
Borrelia burgdorferi induction of indoleamine 2,3‐dioxygenase byhuman immune cells correlates with pathogenesis, results in DCactivation, and requires TLR7 signaling and type I and type IIinterferons.
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