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A river runs through it: how autophagy, senescence, and phagocytosis could be linked to phospholipase D by Wnt signaling
Author(s) -
GomezCambronero Julian,
Kantonen Samuel
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2vmr0214-120rr
Subject(s) - autophagy , microbiology and biotechnology , biology , phagosome , senescence , autophagosome , pi3k/akt/mtor pathway , becn1 , cell , programmed cell death , phospholipase d , signal transduction , phagocytosis , biochemistry , apoptosis
Review on how autophagy in leukocytes leads to a new mechanism involving phospholipase D and the Wnt pathway, when deregulated, can have pathophysiological consequences.