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Pleiotropic effects of extended blockade of CSF1R signaling in adult mice
Author(s) -
Sauter Kristin A.,
Pridans Clare,
Sehgal Anuj,
Tsai Yi Ting,
Bradford Barry M.,
Raza Sobia,
Moffat Lindsey,
Gow Deborah J.,
Beard Philippa M.,
Mabbott Neil A.,
Smith Lee B.,
Hume David A.
Publication year - 2014
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.2a0114-006r
Subject(s) - biology , endocrinology , spleen , medicine , homeostasis , blockade , testosterone (patch) , phenotype , kidney , receptor , immunology , gene , genetics
Prolonged anti‐CSF1R prevents age‐dependent bone loss in female mice, without the phenotypic consequences of the CSF1R and CSF1 null mutations.

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