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Technical Advance: Generation of human pDC equivalents from primary monocytes using Flt3‐L and their functional validation under hypoxia
Author(s) -
Sekar Divya,
Brüne Bernhard,
Weigert Andreas
Publication year - 2010
Publication title -
journal of leukocyte biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.819
H-Index - 191
eISSN - 1938-3673
pISSN - 0741-5400
DOI - 10.1189/jlb.0809543
Subject(s) - biology , hypoxia (environmental) , equivalent , monocyte , primary (astronomy) , immunology , microbiology and biotechnology , biochemistry , computational biology , oxygen , chemistry , physics , organic chemistry , astronomy
Method for the generation of human pDC equivalents ex vivo from primary monocytes, whose differentiation can be manipulated by environmental stimuli such as hypoxia.