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Background Achieving food security is a global priority and a concern for most African countries, including Ghana. Food systems providing varied and healthy diets without compromising the natural resource base, such as integrated crop–livestock diversification, are important for development planning and policy. Using cross-sectional data obtained from 1284 smallholder households in northern Ghana, we used a double-censored Tobit model in a conditional mixed-process (CMP) framework to estimate the impact of crop diversification on household food security. Results The results showed that household-specific, socioeconomic, and institutional factors influence crop–livestock diversification and food security in northern Ghana. Moreover, we found that higher intensity of crop–livestock diversification translates into a greater probability of achieving food security. Conclusions Crop–livestock diversification is essential to Ghana’s pursuit of the zero-hunger global agenda as it enhances food security without adversely affecting biodiversity and ecosystem health. Therefore, it should be incorporated into Ghana’s ongoing agricultural programme dubbed, planting and rearing for food and jobs.

Crop–livestock diversification in the mixed farming systems: implication on food security in Northern Ghana