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Objective   Klebsiella pneumoniae  is one of most opportunistic pathogens that can be related to nosocomial infections. Increased acquisitions of multidrug resistance in this bacterium as well as the transfer of genes to other strains have caused concern. Integrons play key role in the acquisition and the spread of resistance genes. The aim of this study was evaluated the frequency of resistance genes  sulI ,  sulII ,  tetA ,  tetB,  class I ( intI  gene), class II integrons ( intII  gene) and the association between multidrug resistance and the presence of integrons in  K. pneumoniae .    Results  Antibiotics susceptibility test was performed on 126 of  K. pneumoniae  isolates. Also, DNA extraction was done and genes were detected using PCR method. In this study, 67 isolates (53%), carrying both the  sulI  and  sulII  genes. Forty-five percent tetracycline-resistant isolates were  tetA  or  tetB  positive. The prevalence of  intI  gene was 96%, while only sixteen isolate harboring  intII  gene (12.5%). Our results showed the high prevalence of integrons in MDR  K. pneumoniae , indicating the important role of these genes in the transmission of antibiotic resistance.    Supplementary Information  The online version contains supplementary material available at 10.1186/s13104-021-05748-9.

Detection of mobile genetic elements in multidrug-resistant Klebsiella pneumoniae isolated from different infection sites in Hamadan, west of Iran