Open AccessPlatelet lamellipodium formation is not required for thrombus formation and stability
Author(s) -
Yvonne Schurr,
Andreas Sperr,
Julia Volz,
Sarah Beck,
Lucy Reil,
Charly Kusch,
Patrick Eiring,
Sheila Bryson,
Markus Sauer,
Bernhard Nieswandt,
Laura M. Machesky,
Markus Bender
Publication year - 2019
Publication title -
blood
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.515
H-Index - 465
eISSN - 1528-0020
pISSN - 0006-4971
DOI - 10.1182/blood.2019002105
Subject(s) - lamellipodium , filopodia , pseudopodia , platelet , microbiology and biotechnology , platelet activation , thrombus , chemistry , platelet adhesiveness , biology , actin , cytoskeleton , immunology , biochemistry , cell , medicine , platelet aggregation
Key Points Cyfip1 plays a crucial role for branching of actin filaments and for lamellipodium formation. Lamellipodium formation is not required for the formation of a hemostatic plug or thrombus.
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