Hypertension and incident cardiovascular events following ibrutinib initiation
Author(s) -
Tyler Dickerson,
Tracy Wiczer,
Allyson Waller,
J Philippon,
Kyle Porter,
Devin Haddad,
Avirup Guha,
Kerry A. Rogers,
Seema A. Bhat,
John C. Byrd,
Jennifer A. Woyach,
Farrukh T. Awan,
Daniel Addison
Publication year - 2019
Publication title -
blood
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.515
H-Index - 465
eISSN - 1528-0020
pISSN - 0006-4971
DOI - 10.1182/blood.2019000840
Subject(s) - ibrutinib , medicine , intensive care medicine , leukemia , chronic lymphocytic leukemia
In a retrospective analysis, Dickerson et al report that the incidence of hypertension in patients treated with ibruitinib is nearly 80% and is associated with an increased rate of adverse cardiovascular events, primarily atrial fibrillation. Cardiac events can be reduced by treating the hypertension.
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