Open AccessMilan ultrasound criteria are accurate in assessing disease activity in ulcerative colitis: external validation
Author(s) -
Allocca Mariangela,
Filippi Elisabetta,
Costantino Andrea,
Bonovas Stefanos,
Fiorino Gionata,
Furfaro Federica,
PeyrinBiroulet Laurent,
Fraquelli Mirella,
Caprioli Flavio,
Danese Silvio
Publication year - 2021
Publication title -
ueg journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.667
H-Index - 35
eISSN - 2050-6414
pISSN - 2050-6406
DOI - 10.1177/2050640620980203
Subject(s) - medicine , ulcerative colitis , gastroenterology , inflammatory bowel disease , ultrasound , confidence interval , colonoscopy , tertiary referral hospital , area under the curve , endoscopic ultrasound , endoscopy , disease , radiology , retrospective cohort study , colorectal cancer , cancer
Abstract Introduction The aim of this study was to provide an external validation of bowel ultrasound (US) predictors of activity in ulcerative colitis (UC) and quantitative Milan Ultrasound Criteria (MUC). Methods Forty‐three consecutive patients with UC (16 in endoscopic remission and 27 with endoscopic activity) underwent bowel US and colonoscopy in a tertiary referral inflammatory bowel disease unit. Results An MUC score >6.2 discriminated patients with active versus non‐active UC with a sensitivity of 0.85 (95% confidence interval (CI) 0.66–0.96), specificity of 0.94 (95% CI 0.70–0.99) and an area under the curve of 0.902 (95% CI 0.772–0.971) in complete agreement with the derivation study. Conclusion The external validation of MUC confirms that it is an accurate tool for assessing disease activity in patients with UC.