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Studies suggest that folic acid intake influences the occurrence of low birthweight and preterm delivery. Since 1998, there has been compulsory fortification of flour and other grains with folic acid in the U.S. The objective of this study was to investigate the frequencies of low birthweight and preterm delivery after mandatory folic acid fortification among approximately six million California births.

Occurrence of Low Birthweight and Preterm Delivery among California Infants before and after Compulsory Food Fortification with Folic Acid