Open AccessLRRC10 (Leucine‐Rich Repeat Containing Protein 10) and REEP5 (Receptor Accessory Protein 5) as Novel Regulators of Cardiac Excitation‐Contraction Coupling Structure and Function
Author(s) -
Chiamvimonvat Nipavan,
Song LongSheng
Publication year - 2018
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.008260
Subject(s) - medicine , contraction (grammar) , excitation–contraction coupling , receptor , leucine , cardiology , microbiology and biotechnology , biophysics , biochemistry , amino acid , myocyte , biology
In cardiomyocytes, excitation–contraction (E‐C) coupling is the fundamental mechanism governing the contractile function of the heart, by which working ventricular myocytes generate sufficient contractile force to pump blood throughout the body.[1][1] In the past several decades, numerous