Open AccessApoB/ApoA‐I Ratio is Associated With Faster Hemodynamic Progression of Aortic Stenosis: Results From the PROGRESSA (Metabolic Determinants of the Progression of Aortic Stenosis) Study
Author(s) -
Tastet Lionel,
Capoulade Romain,
Shen Mylène,
Clavel MarieAnnick,
Côté Nancy,
Mathieu Patrick,
Arsenault Marie,
Bédard Élisabeth,
Tremblay Alexe,
Samson Marilie,
Bossé Yohan,
Dumesnil Jean G.,
Arsenault Benoit J.,
Beaudoin Jonathan,
Bernier Mathieu,
Després JeanPierre,
Pibarot Philippe
Publication year - 2018
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.007980
Subject(s) - medicine , apolipoprotein b , cardiology , hemodynamics , stenosis , aortic valve stenosis , cohort , cholesterol
Previous studies reported that middle-aged patients with atherogenic lipoprotein-lipid profile exhibit faster progression of aortic valve stenosis (AS). The ratio of apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) reflects the balance between atherogenic and anti-atherogenic lipoproteins. The aim of this study was to examine the association between apoB/apoA-I ratio and AS hemodynamic progression and to determine whether this association varies according to age.