Open AccessInflammation and Aortic Stiffness: An Individual Participant Data Meta‐Analysis in Patients With Inflammatory Bowel Disease
Author(s) -
Zanoli Luca,
Boutouyrie Pierre,
Fatuzzo Pasquale,
Granata Antonio,
Lentini Paolo,
Oztürk Kadir,
Cappello Maria,
Theocharidou Eleni,
Tuttolomondo Antonino,
Pinto Antonio,
Cammà Calogero,
Licata Anna,
Blanco Julien,
Rastelli Stefania,
Inserra Gaetano,
Castellino Pietro,
Laurent Stephane
Publication year - 2017
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.007003
Subject(s) - medicine , confidence interval , pulse wave velocity , inflammatory bowel disease , ulcerative colitis , arterial stiffness , confounding , meta analysis , gastroenterology , disease , blood pressure
The recent finding that aortic pulse wave velocity (aPWV) is increased in patients with inflammatory bowel disease may explain why the cardiovascular risk is increased despite the low prevalence of traditional cardiovascular risk factors. We aimed to test whether inflammation is associated with aortic stiffening in this setting after adjustment for major confounders and to perform subgroup analyses.