Open AccessProhormones in the Early Diagnosis of Cardiac Syncope
Author(s) -
Badertscher Patrick,
Nestelberger Thomas,
Lavallaz Jeanne du Fay,
Than Martin,
Morawiec Beata,
Kawecki Damian,
Miró Òscar,
López Beatriz,
MartinSanchez F. Javier,
Bustamante José,
Geigy Nicolas,
Christ Michael,
Di Somma Salvatore,
Peacock W. Frank,
Cullen Louise,
Sarasin François,
Flores Dayana,
Tschuck Michael,
Boeddinghaus Jasper,
Twerenbold Raphael,
Wildi Karin,
Sabti Zaid,
Puelacher Christian,
Rubini Giménez Maria,
Kozhuharov Nikola,
Shrestha Samyut,
Strebel Ivo,
Rentsch Katharina,
Keller Dagmar I.,
Poepping Imke,
Buser Andreas,
Kloos Wanda,
Lohrmann Jens,
Kuehne Michael,
Osswald Stefan,
Reichlin Tobias,
Mueller Christian
Publication year - 2017
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.117.006592
Subject(s) - medicine , copeptin , cardiology , syncope (phonology) , emergency department , confidence interval , prohormone , natriuretic peptide , atrial fibrillation , heart failure , vasopressin , psychiatry , hormone
The early detection of cardiac syncope is challenging. We aimed to evaluate the diagnostic value of 4 novel prohormones, quantifying different neurohumoral pathways, possibly involved in the pathophysiological features of cardiac syncope: midregional-pro-A-type natriuretic peptide (MRproANP), C-terminal proendothelin 1, copeptin, and midregional-proadrenomedullin.