Open AccessEarly Denervation and Later Reinnervation of the Heart Following Cardiac Transplantation: A Review
Author(s) -
Awad Morcos,
Czer Lawrence S. C.,
Hou Margaret,
Golshani Sarah S.,
Goltche Michael,
De Robertis Michele,
Kittleson Michelle,
Patel Jignesh,
Azarbal Babak,
Kransdorf Evan,
Esmailian Fardad,
Trento Alfredo,
Kobashigawa Jon A.
Publication year - 2016
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.116.004070
Subject(s) - medicine , reinnervation , denervation , heart transplantation , transplantation , cardiology , surgery
Heart transplantation (HTx) surgically interrupts the parasympathetic vagal neurons and the intrinsic postganglionic sympathetic nerve fibers traveling from the stellate ganglia to the myocardium, causing axonal Wallerian degeneration and thus extrinsic cardiac denervation.[1][1], [2][2], [3][3], [4