Open AccessNeurohormonal Activation After Atrial Fibrillation Initiation in Patients Eligible for Catheter Ablation: A Randomized Controlled Study
Author(s) -
Charitakis Emmanouil,
Walfridsson Håkan,
Nylander Eva,
Alehagen Urban
Publication year - 2016
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.116.003957
Subject(s) - medicine , atrial fibrillation , cardiology , natriuretic peptide , copeptin , coronary sinus , catheter ablation , atrial natriuretic peptide , radiofrequency ablation , randomized controlled trial , biomarker , ablation , heart failure , biochemistry , vasopressin , chemistry
Biomarker activation in atrial fibrillation (AF) has been widely studied, but the immediate effect of AF initiation remains unclear. We studied the effect of AF initiation on 2 cardiac biomarkers: the N-terminal fragment of the proB-type natriuretic peptide (NT-proBNP), the midregional fragment of the N-terminal of pro-atrial natriuretic peptide (MR-proANP), and 2 extracardiac biomarkers-the copeptin and the midregional portion of proadrenomedullin (MR-proADM).