
Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF – TIMI 48 Trial
Author(s) -
Kato Eri Toda,
Giugliano Robert P.,
Ruff Christian T.,
Koretsune Yukihiro,
Yamashita Takeshi,
Kiss Robert Gabor,
Nordio Francesco,
Murphy Sabina A.,
Kimura Tetsuya,
Jin James,
Lanz Hans,
Mercuri Michele,
Braunwald Eugene,
Antman Elliott M.
Publication year - 2016
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.116.003432
Subject(s) - medicine , edoxaban , atrial fibrillation , timi , warfarin , hazard ratio , stroke (engine) , cardiology , randomized controlled trial , myocardial infarction , percutaneous coronary intervention , confidence interval , dabigatran , mechanical engineering , engineering
Elderly patients with atrial fibrillation are at higher risk of both ischemic and bleeding events compared to younger patients. In a prespecified analysis from the ENGAGE AF-TIMI 48 trial, we evaluate clinical outcomes with edoxaban versus warfarin according to age.