Open AccessDesign and Rationale of the Best Endovascular Versus Best Surgical Therapy for Patients With Critical Limb Ischemia (BEST‐CLI) Trial
Author(s) -
Menard Matthew T.,
Farber Alik,
Assmann Susan F.,
Choudhry Niteesh K.,
Conte Michael S.,
Creager Mark A.,
Dake Michael D.,
Jaff Michael R.,
Kaufman John A.,
Powell Richard J.,
Reid Diane M.,
Siami Flora Sandra,
Sopko George,
White Christopher J.,
Rosenfield Kenneth
Publication year - 2016
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.116.003219
Subject(s) - medicine , critical limb ischemia , randomized controlled trial , revascularization , clinical endpoint , amputation , cohort , clinical trial , surgery , quality of life (healthcare) , adverse effect , physical therapy , nursing , myocardial infarction
Critical limb ischemia (CLI) is increasing in prevalence, and remains a significant source of mortality and limb loss. The decision to recommend surgical or endovascular revascularization for patients who are candidates for both varies significantly among providers and is driven more by individual preference than scientific evidence.