Open AccessPlasma Glycine and Risk of Acute Myocardial Infarction in Patients With Suspected Stable Angina Pectoris
Author(s) -
Ding Yunpeng,
Svingen Gard F. T.,
Pedersen Eva R.,
Gregory Jesse F.,
Ueland Per M.,
Tell Grethe S.,
Nygård Ottar K.
Publication year - 2016
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.115.002621
Subject(s) - medicine , myocardial infarction , diabetes mellitus , cardiology , unstable angina , apolipoprotein b , hazard ratio , angina , cholesterol , body mass index , endocrinology , confidence interval
Glycine is an amino acid involved in antioxidative reactions, purine synthesis, and collagen formation. Several studies demonstrate inverse associations of glycine with obesity, hypertension, and diabetes mellitus. Recently, glycine-dependent reactions have also been linked to lipid metabolism and cholesterol transport. However, little evidence is available on the association between glycine and coronary heart disease. Therefore, we assessed the association between plasma glycine and acute myocardial infarction (AMI).