Open AccessIncremental Value of the CRUSADE , ACUITY , and HAS ‐ BLED Risk Scores for the Prediction of Hemorrhagic Events After Coronary Stent Implantation in Patients Undergoing Long or Short Duration of Dual Antiplatelet Therapy
Author(s) -
Costa Francesco,
Tijssen Jan G.,
Ariotti Sara,
Giatti Sara,
Moscarella Elisabetta,
Guastaroba Paolo,
De Palma Rossana,
Andò Giuseppe,
Oreto Giuseppe,
Zijlstra Felix,
Valgimigli Marco
Publication year - 2015
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.115.002524
Subject(s) - medicine , hazard ratio , area under the curve , myocardial infarction , framingham risk score , stroke (engine) , cardiology , surgery , confidence interval , mechanical engineering , disease , engineering
Multiple scores have been proposed to stratify bleeding risk, but their value to guide dual antiplatelet therapy duration has never been appraised. We compared the performance of the CRUSADE (Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the ACC/AHA Guidelines), ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy), and HAS-BLED (Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol Concomitantly) scores in 1946 patients recruited in the Prolonging Dual Antiplatelet Treatment After Grading Stent-Induced Intimal Hyperplasia Study (PRODIGY) and assessed hemorrhagic and ischemic events in the 24- and 6-month dual antiplatelet therapy groups.