Open AccessThioredoxin Reductase 2 (Txnrd2) Regulates Mitochondrial Integrity in the Progression of Age‐Related Heart Failure
Author(s) -
Yoshioka Jun
Publication year - 2015
Publication title -
journal of the american heart association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.494
H-Index - 85
ISSN - 2047-9980
DOI - 10.1161/jaha.115.002278
Subject(s) - medicine , heart failure , thioredoxin reductase , cardiology , mitochondrion , oxidative stress , bioinformatics , thioredoxin , physiology , microbiology and biotechnology , biology
Aging is a multifactorial process that is characterized by the accumulation of damaged cellular components and that leads progressively to deterioration of biological functions.[1][1] Recently, increased cellular production of reactive oxygen species (ROS) and decreased removal of oxidized proteins