Open AccessКРОС-ПЛАТФОРМНЕ ОБ’ЄДНАННЯ ДАНИХ МІКРОМАСИВ-ЕКСПЕРИМЕНТІВ ТА ЙОГО ВПЛИВ НА ЗНАЧЕННЯ ГЕННОЇ ЕКСПРЕСІЇ ПРИ АНАЛІЗІ ЗРАЗКІВ РАКОВИХ ПУХЛИН МОЛОЧНОЇ ЗАЛОЗИ ЛЮДИНИ
Author(s) -
Alina Frolova,
В. С. Бондаренко,
M. Yu. Obolenska
Publication year - 2016
Publication title -
medična ìnformatika ta ìnženerìâ
Language(s) - English
Resource type - Journals
eISSN - 1997-7468
pISSN - 1996-1960
DOI - 10.11603/mie.1996-1960.2016.2.6476
Subject(s) - computer science , microarray analysis techniques , data mining , microarray , process (computing) , throughput , biology , gene , gene expression , genetics , telecommunications , wireless , operating system
. Currently advances in different fields of biology and medicine accumulated large amount of high-throughput microarray datasets. It allows comparing, merging and analyzing such data in order to get more informative and statistically significant results. However, the process of cross-platform microarray data integration is complicated by different platform designs, that is the kind of probes used, the hybridization paradigm, the labeling and production methods. Such characteristics of microarray platforms should be considered when analyzing datasets from one study and even more when merging datasets.