Open AccessA Case of Acute Myeloid Leukemia-Associated Necrotizing Sweet Syndrome
Author(s) -
Strong Jennifer,
Zhou Albert E.,
Alkaabba Fahad,
Soldin Danielle,
Moon Joanne,
Alharthy Hanan,
Syed Owais,
Liu Yuchen,
Turney Kathryn,
Markidan Janina,
Malone Laura,
Lee Seung Tae,
DeRosa Peter
Publication year - 2022
Publication title -
case reports in dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.338
H-Index - 18
ISSN - 1662-6567
DOI - 10.1159/000527597
Subject(s) - single case
Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, is a rare painful skin condition that is characterized by hyperpyrexia, peripheral blood and skin neutrophilia, and edematous skin lesions. Necrotizing SS (NSS) is a severe and locally aggressive condition that histopathologically resembles a necrotizing soft tissue infection. As opposed to necrotizing soft tissue infections, NSS responds to systemic steroids. SS is divided into three subtypes: classical SS, malignancy-associated SS, and drug-induced SS. Within the malignancy-associated SS subtype, both solid tumor and hematologic malignancies have been precursors to developing SS. Here, we present a case of acute myeloid leukemia-associated NSS.