Open AccessA Case of Acquired von Willebrand Syndrome Complicated by Acute Myelomonocytic Leukemia
Author(s) -
Fukatsu Masahiko,
Ohkawara Hiroshi,
Takahashi Hiroshi,
Mori Hirotaka,
Yaginuma Mai,
Endo Mamiko,
Shichishima-Nakamura Akiko,
Sano Takahiro,
Harada-Shirado Kayo,
Kimura Satoshi,
Ogawa Kazuei,
Hashimoto Yuko,
Ikezoe Takayuki
Publication year - 2021
Publication title -
case reports in oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 19
ISSN - 1662-6575
DOI - 10.1159/000517439
Subject(s) - case report
We here report a 21-year-old male who presented with acute myelomonocytic leukemia (AMML) associated with acquired von Willebrand syndrome (AVWS). To our knowledge, this is the first case of AVWS caused by AMML. In our case, following remission-induction chemotherapy combined with idarubicin and cytarabine, the patient showed remarkable improvement of bleeding symptoms due to AVWS. Moreover, after an allogeneic stem cell transplantation from a sibling donor, both AMML and AVWS maintain complete remission.