Open AccessSevere Generalized Bullous Fixed Drug Eruption Treated with Cyclosporine: A Case Report and Literature Review
Author(s) -
Barootes Hailey C.,
Peebles Erin R.,
Matsui Doreen,
Rieder Michael,
Abuzgaia Awatif,
Mohammed Javed A.
Publication year - 2021
Publication title -
case reports in dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.338
H-Index - 18
ISSN - 1662-6567
DOI - 10.1159/000513469
Subject(s) - case and review
Generalized bullous fixed drug eruptions (GBFDEs) are rare in the paediatric population. We present the case of a 7-year-old girl with GBFDE believed to be secondary to oral ibuprofen, who experienced rapid resolution of lesions and cessation of blistering with a 3-week course of oral cyclosporine. To the best of our knowledge, this is the first report of a paediatric case of GBFDE treated with cyclosporine. In our report, we review published cases of GBFDE in children, and all adult cases managed with cyclosporine.