Open AccessIntraocular Tuberculosis: A Challenging Case Mimicking Wet Age-Related Macular Degeneration
Author(s) -
Interlandi Emanuela,
Pellegrini Francesco,
Pavesio Carlos,
De Luca Marco,
De Marco Rocco,
Papayannis Alessandro,
Mandarà Erika,
Cuna Alessandra,
Cirone Daniele,
Ciabattoni Cristina,
Liberali Tatiana,
Zappacosta Antonio,
Latanza Loredana
Publication year - 2021
Publication title -
case reports in ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.299
H-Index - 17
ISSN - 1663-2699
DOI - 10.1159/000512578
Subject(s) - case report
An otherwise healthy 72-year-old Chinese patient diagnosed with exudative age-related macular degeneration and decreased vision in left eye was fully investigated. The retrospective analysis of past multimodal imaging revealed bilateral severe choroidal neovascularization and choroiditis associated with a positive tuberculin skin testing and interferon-gamma release assay (QuantiFERON-TB Gold – Cellestis®, Chadstone, VIC, Australia) suggestive of latent ocular tuberculosis. The variable presentation and tests’ results interpretation represent the greatest limitations in understanding and treating intraocular TB (IOTB). This may present without any other systemic symptoms, the intraocular tissues are of limited access to biopsies and other tests, including imaging and immunological tests, are of relative value. This case highlights how variable may be the presentation of IOTB, which can be easily misdiagnosed leading to a delayed treatment and worse prognosis.