z-logo
open-access-imgOpen Access
Spontaneous Regression of Advanced Hepatocellular Carcinoma
Author(s) -
Sonbare Dhiraj J.,
Bandi Rupal,
Sharma Vivek,
Cacciarelli Thomas,
Shaikh Obaid S.
Publication year - 2020
Publication title -
case reports in gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 18
ISSN - 1662-0631
DOI - 10.1159/000508847
Subject(s) - case and review
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. The tumor carries poor prognosis with curative therapeutic options limited to surgical resection, tumor ablation, and liver transplantation. Rarely, there is spontaneous regression of the tumor. We describe the case of a 74-year-old male with cirrhosis from non-alcoholic steatohepatitis who developed advanced HCC that was associated with tumor invasion of the portal vein and marked elevation of serum alfa-fetoprotein level. The patient received no cancer-specific therapy. However, 1 year after the initial diagnosis, he was noted to have complete regression of the tumor. In this report, we discuss possible mechanisms of spontaneous tumor regression and its therapeutic implications.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here