Open AccessLung Adenocarcinoma during Pregnancy: 11-Year Follow-Up
Author(s) -
Acosta Rojas Angel,
Collazo-Lorduy Ana,
Remon Jordi,
Hernando Requejo Ovidio,
Jiménez-Munarriz Beatriz,
Rubio Rodríguez María Carmen,
De Castro Javier
Publication year - 2020
Publication title -
case reports in oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 19
ISSN - 1662-6575
DOI - 10.1159/000508360
Subject(s) - case report
The incidence of lung cancer during pregnancy is rising due to the high rate of smokers in young women and the late mean age of pregnancy; in addition, considering that the patients are young women with a higher incidence of molecular alterations, molecular testing in lung adenocarcinoma should always be performed, even in pregnancy. Here, we report the case of a lung adenocarcinoma diagnosed during pregnancy with a long survival who benefitted from brain radiotherapy, conventional chemotherapy, and ALK TKI-targeted treatment. It reveals the safety of whole brain radiotherapy during pregnancy and consideration of other brain radiation techniques even in palliative cases, which should be personalized and managed by a multidisciplinary team. However, upfront management of brain metastasis in ALK-positive patients remains unresolved.