Open AccessAmiodarone-Induced Acute Liver Injury
Author(s) -
Essrani Rajesh,
Mehershahi Shehriyar,
Essrani Rajesh Kumar,
Ravi Shri Jai Kirshan,
Bhura Sajeer,
Sudhakaran Anuraj,
Hossain Muhammad,
Mehmood Asif
Publication year - 2020
Publication title -
case reports in gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.247
H-Index - 18
ISSN - 1662-0631
DOI - 10.1159/000506184
Subject(s) - single case
Amiodarone is a lipophilic structure with a half-life of 25–100 days. Long-term oral amiodarone is associated with photosensitivity, thyroid dysfunction, and pulmonary and hepatic toxicity. Intravenous amiodarone can lead to sweating, heating sensation, nausea, phlebitis at the injection site, and rarely acute hepatitis. This is a compelling case of a 60-year-old male who developed acute liver injury 24–36 h after starting amiodarone. All the possible causes of acute liver injury were ruled out, and his liver enzymes improved after discontinuing amiodarone.