Open AccessAn Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid
Author(s) -
Madoka Takafuji,
Atsushi Tanemura,
Ichiro Katayama
Publication year - 2019
Publication title -
case reports in dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.338
H-Index - 18
ISSN - 1662-6567
DOI - 10.1159/000499031
Subject(s) - dermatology , cosmetics , ascorbic acid , discontinuation , medicine , cheek , pathology , surgery , chemistry , food science
We report the case of a 73-year-old woman with leukoderma induced by cosmetics containing ascorbic acid. She had noticed the sudden appearance of a hypopigmented macule on the cheek within 1 month after use of the cosmetics with the brand name Obaji C Serum. No history of use of rhododenol-containing cosmetics was declared. Histopathological analysis revealed that the number of matured melanocytes was apparently decreased, and T lymphocytes abundantly infiltrated mainly the perifollicular region. In addition to the discontinuation of using Obaji C Serum, phototherapy by excimer light was noticeably effective for repigmentation. To our knowledge, there has been no other report so far showing hypopigmented lesions induced by this cosmetic.