Open AccessT-Cadherin Expression in Actinic Keratosis Transforming to Invasive Squamous Cell Carcinoma
Author(s) -
Stanislaw A. Buechner,
Thérèse J. Resink
Publication year - 2019
Publication title -
dermatopathology
Language(s) - English
Resource type - Journals
ISSN - 2296-3529
DOI - 10.1159/000495609
Subject(s) - actinic keratosis , cadherin , pathology , basal cell carcinoma , malignant transformation , basal cell , basal (medicine) , keratosis , immunohistochemistry , staining , carcinoma , medicine , biology , cell , genetics , insulin
Clinical and histological features of actinic keratosis (AK) cannot predict malignant transformation to invasive squamous cell carcinoma (iSCC) in individual lesions. We investigated whether patterns/distribution of T-cadherin in AK lesions have biomarker value in predicting transformation to iSCC.