Open AccessSuccessful Treatment with Taxane-Based Chemotherapy in Advanced Sebaceous Carcinoma: A Case Report and Literature Review
Author(s) -
Shuji Ota,
Takahiko Sakamoto,
Ryosuke Ochiai,
Takahiro Haruyama,
Masashi Ishihara,
Maika Natsume,
Yoko Fukasawa,
Shigeru Tanzawa,
Ryo Usui,
Takeshi Honda,
Yasuko Ichikawa,
Kiyotaka Watanabe,
Yuko Sasajima,
Atsushi Mizota,
Nobuhiko Seki
Publication year - 2019
Publication title -
case reports in oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.365
H-Index - 19
ISSN - 1662-6575
DOI - 10.1159/000493850
Subject(s) - taxane , medicine , docetaxel , carboplatin , chemotherapy , oncology , paclitaxel , regimen , cancer , breast cancer , cisplatin
For sebaceous carcinoma (SC), a rare malignant tumor, no standard chemotherapy regimen for patients with distant metastasis has been studied. We experienced a case of eyelid SC with multiple lung metastases that responded to combination chemotherapy with carboplatin and paclitaxel with 11-month progression-free survival (PFS). This patient also responded to second-line treatment with docetaxel, another taxane, with 7-month PFS, resulting in at least 18 months of survival at the time of reporting. This report shows that taxane-based chemotherapy may be effective for advanced SC, for which no standard therapy has been established.