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A cryptic inv(16)(p13.3q24.3) encoding the CBFA2T3-GLIS2 fusion is associated with poor outcome in infants with acute megakaryocytic leukemia. We aimed to broaden our understanding of the pathogenesis of this fusion through transcriptome profiling.

clinical cancer research

Comprehensive Transcriptome Profiling of Cryptic <i>CBFA2T3–GLIS2</i> Fusion–Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study

Comprehensive Transcriptome Profiling of Cryptic CBFA2T3–GLIS2 Fusion–Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study