Open AccessSynthetic Apparent Diffusion Coefficient for High b-Value Diffusion-Weighted MRI in Prostate
Author(s) -
Prativa Sahoo,
Russell C. Rockne,
Jung Alexander,
Pradeep Kumar Gupta,
Ram K.S. Rathore,
Rakesh Kumar Gupta
Publication year - 2020
Publication title -
prostate cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.377
H-Index - 11
eISSN - 2090-3111
pISSN - 2090-312X
DOI - 10.1155/2020/5091218
Subject(s) - prostate cancer , medicine , prostate , diffusion mri , effective diffusion coefficient , nuclear medicine , radiology , cancer , magnetic resonance imaging
Purpose It has been reported that diffusion-weighted imaging (DWI) with ultrahigh b -value increases the diagnostic power of prostate cancer. DWI with higher b -value increases the diagnostic power of prostate cancer. DWI with higher b -value increases the diagnostic power of prostate cancer. DWI with higher b -value increases the diagnostic power of prostate cancer. DWI with higher Materials and Methods . Fifteen patients (7 malignant and 8 benign) were included in this study retrospectively with the institutional ethical committee approval. All images were acquired at a 3T MR scanner. The ADC values were calculated using a monoexponential model. Synthetic ADC (sADC) for higher b -value increases the diagnostic power of prostate cancer. DWI with higherResults No significant difference was observed between actual ADC and sADC for b -value increases the diagnostic power of prostate cancer. DWI with higher p =0.002, paired t -test) in sDWI as compared to DWI. Malignant lesions showed significantly lower sADC as compared to benign lesions ( p =0.002, paired t -test) in sDWI as compared to DWI. Malignant lesions showed significantly lower sADC as compared to benign lesions ( Discussion / Conclusion Our initial investigation suggests that the ADC values corresponding to higher b -value can be computed using log-linear relationship derived from lower b -values ( b ≤ 1000). Our method might help clinicians to decide the optimal b -value for prostate lesion identification. b -value increases the diagnostic power of prostate cancer. DWI with higher b -value increases the diagnostic power of prostate cancer. DWI with higher b -value increases the diagnostic power of prostate cancer. DWI with higher b -value increases the diagnostic power of prostate cancer. DWI with higher