
Systemic Lupus Erythematosus Presented with Bilateral Orbital Edema and Negative Serology
Author(s) -
Manal Rashid Al-Khaldi,
Manal Alsabbagh
Publication year - 2019
Publication title -
case reports in rheumatology
Language(s) - English
Resource type - Journals
eISSN - 2090-6889
pISSN - 2090-6897
DOI - 10.1155/2019/7140534
Subject(s) - medicine , serology , dermatology , histopathology , edema , hydroxychloroquine , systemic lupus erythematosus , pathology , surgery , immunology , disease , covid-19 , infectious disease (medical specialty) , antibody
Isolated bilateral periorbital edema with negative serology is an extremely rare presentation of cutaneous lupus erythematosus that may lead to eyelid scarring, infection, or even corneal involvement. The treatment usually comprises a combination of hydroxychloroquine and a tapering dose of systemic steroids. Patients require long-term follow-up as they may develop systemic lupus erythematosus with positive serology later in life. We report a case of a 32-year-old female who presented with chronic bilateral periorbital edema, and the histopathology confirmed cutaneous lupus erythematosus.