Open AccessUpdate on Myopia Risk Factors and Microenvironmental Changes
Author(s) -
Valeria Coviltir,
Miruna Burcel,
Alina Popa-Cherecheanu,
Cătălina Ionescu,
Dana Dăscălescu,
Vasile Potop,
Marian Burcea
Publication year - 2019
Publication title -
journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 40
eISSN - 2090-0058
pISSN - 2090-004X
DOI - 10.1155/2019/4960852
Subject(s) - medicine , pathogenesis , computational biology , focus (optics) , bioinformatics , biology , pathology , physics , optics
The focus of this update is to emphasize the recent advances in the pathogenesis and various molecular key approaches associated with myopia in order to reveal new potential therapeutic targets. We review the current evidence for its complex genetics and evaluate the known or candidate genes and loci. In addition, we discuss recent investigations regarding the role of environmental factors. This paper also covers current research aimed at elucidating the signaling pathways involved in the pathogenesis of myopia.