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Ciclosporin in canine dermatology: a decade of comfort
Author(s) -
DeBoer Douglas J.
Publication year - 2014
Publication title -
veterinary record
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 99
eISSN - 2042-7670
pISSN - 0042-4900
DOI - 10.1136/vr.g2152
Subject(s) - ciclosporin , atopic dermatitis , medicine , dermatology , surgery , transplantation
I OFTEN begin a lecture on atopic dermatitis by reflecting what on our very limited (perhaps even naive) view of the pathogenesis of this challenging condition was 20 years ago, and how dramatically our understanding has improved over this same time. Many of us remember a time when ‘cytokine’ was a new and unfamiliar term, and the newest trend in therapy was cautious and prudent use of short-term oral glucocorticoids rather than long-acting injections. Fast-forward to today, where interfering with cytokine pathways is standard treatment, and research continues to elucidate pathways and provide new targets for drugs aimed at inflammatory skin diseases.The authors of these reviews provide a comprehensive overview of ciclosporin and its uses in veterinary dermatology. The drug has become a mainstay for treatment of canine atopic dermatitis, and has, …