Open AccessMorphine Enhances HIV Infection of Human Blood Mononuclear Phagocytes through Modulation of β-Chemokines and CCR5 Receptor
Author(s) -
Changjiang Guo,
Yuan Li,
Sha Tian,
Xu Wang,
Steven D. Douglas,
WenZhe Ho
Publication year - 2002
Publication title -
journal of investigative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.879
H-Index - 66
eISSN - 1708-8267
pISSN - 1081-5589
DOI - 10.1136/jim-50-06-03
Subject(s) - chemokine , peripheral blood mononuclear cell , morphine , human immunodeficiency virus (hiv) , chemokine receptor ccr5 , immunology , medicine , chemokine receptor , pharmacology , chemistry , inflammation , in vitro , biochemistry
Injection drug use remains a significant risk for acquiring HIV infection. The mechanisms by which morphine enhances HIV infection of human immune cells are largely unknown.