
External evaluation of a published population pharmacokinetic model of valproic acid in Thai manic patients
Author(s) -
Janthima Methaneethorn,
Manupat Lohitnavy
Publication year - 2018
Publication title -
european journal of hospital pharmacy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.313
H-Index - 14
eISSN - 2047-9964
pISSN - 2047-9956
DOI - 10.1136/ejhpharm-2018-001653
Subject(s) - valproic acid , pharmacokinetics , mean squared error , medicine , mania , population , nonmem , therapeutic drug monitoring , statistics , bipolar disorder , mathematics , epilepsy , psychiatry , environmental health , lithium (medication)
To evaluate external predictability of a population pharmacokinetic model of valproic acid in Thai patients with mania to ensure its appropriateness for use in other clinical settings.