Open AccessSubcutaneous mass concerning for sarcoma: a peculiar presentation of diffuse large B-cell lymphoma
Author(s) -
John Mayo,
Kenneth Bogenberger,
Thomas Raj,
Jeffrey Reha
Publication year - 2019
Publication title -
bmj case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.231
H-Index - 26
ISSN - 1757-790X
DOI - 10.1136/bcr-2019-229327
Subject(s) - medicine , diffuse large b cell lymphoma , lymphoma , biopsy , sarcoma , presentation (obstetrics) , soft tissue sarcoma , pathological , pathology , radiology , lesion
Diffuse large B-cell lymphoma (DLBCL) can present in a number of different ways, including as a primary cutaneous lesion or at various other extranodal sites. However, it is rare for a DLBCL to present as a clinically subcutaneous mass without visible skin changes or nodal involvement. A 36-year-old man presented with a 4×4×1 cm subcutaneous mass to his shoulder with normal overlying skin which had been enlarging over 6 months. Physical exam and imaging together made a strong case for sarcoma, and the patient underwent a radical resection. The final pathological diagnosis returned as a diffuse B-cell lymphoma (germinal centre type). The patient subsequently healed and tolerated chemotherapy well. DLBCL can masquerade as a soft tissue mass at initial presentation. If the diagnosis is not clear, a biopsy should be pursued.