Open AccessNovel Intertypic Recombinants of Epstein-Barr Virus in the Chinese Population
Author(s) -
Rachel Midgley,
Neil Blake,
Qing Yao,
Debbie Croom-Carter,
Siu Tim Cheung,
Sing-fai Leung,
Anthony Chan,
Philip J. Johnson,
Dolly Huang,
Alan B. Rickinson,
S. P. Lee
Publication year - 2000
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.74.3.1544-1548.2000
Subject(s) - biology , genetics , locus (genetics) , virus , recombination , population , virology , gammaherpesvirinae , gene , herpesviridae , viral disease , demography , sociology
Among 34 Epstein-Barr virus isolates from nonimmunocompromised Chinese donors, we identified three intertypic recombinants with type 1 sequences at the EBNA2 locus and type 2 sequences at some or all of the EBNA3A, -3B, and -3C loci. These appear to have arisen from independent, evolutionarily recent recombination events; such events may be commoner in nonimmunocompromised populations than hitherto imagined.