Open AccessEvidence that the genome of hepatitis A virus consists of single-stranded RNA
Author(s) -
A G Coulepis,
Gregory A. Tannock,
SA Locarnini,
Ian D. Gust
Publication year - 1981
Publication title -
journal of virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.617
H-Index - 292
eISSN - 1070-6321
pISSN - 0022-538X
DOI - 10.1128/jvi.37.1.473-477.1981
Subject(s) - picornaviridae , biology , rna , virology , nucleic acid , virus , hepatitis a virus , enterovirus , genome , picornavirus , genetics , gene
Nucleic acid was extracted from purified hepatitis A virus, radiolabeled with 125I, and shown to consist of single-stranded RNA which sediments at 35S and contains sequences of polyadenylic acid. These findings are consistent with hepatitis A virus being a member of the genus Enterovirus within the family Picornaviridae.
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