English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Helicobacter pylori virulence determinants have not previously been studied in detail in Latin Americans withH. pylori infections. We characterized thevacA (vacuolating cytotoxin gene A) andcagA (cytotoxin-associated gene A) types of more than 400 single-colony isolates from 20 patients in Mexico City. For 17 patientsH. pylori strains of two or more differentvacA genotypes were isolated from gastric biopsy specimens, indicating infection with two or more strains ofH. pylori . The most frequentvacA genotype was s1b/m1.vacA diversity was more marked than that described previously, in that isolates from seven patients had untypeablevacA midregions and isolates from nine patients had type s1 signal sequence coding regions which could not be further subtyped. Previously undescribedvacA type s2/m1 strains were found in five patients. All patients were infected withcagA -positive strains, but occasionally, these coexisted with small numbers ofcagA -negative strains. In conclusion, coinfection with multipleH. pylori strains is common in Mexico, andvacA in these strains is genetically more diverse than has been described in other populations.

Colonization of Mexican Patients by Multiple Helicobacter pylori Strains with Different vacA and cagA Genotypes