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The ribosomal region spanning the two internal transcribed spacer (ITS) regions and the 5.8S ribosomal DNA region was sequenced for asexual, anthropophilic dermatophyte species with morphological similarity toTrichophyton rubrum , as well as for members of the three previously delineated, related major clades in theT. mentagrophytes complex. Representative isolates ofT. raubitschekii ,T. fischeri , andT. kanei were found to have ITS sequences identical to that ofT. rubrum . The ITS sequences ofT. soudanense andT. megninii differed from that ofT. rubrum by only a small number of base pairs. Their continued status as species, however, appears to meet criteria outlined in the population genetics-based cohesion species concept of A. R. Templeton. The ITS sequence ofT. tonsurans differed from that of the biologically distinctT. equinum by only 1 bp, while the ITS sequence of the recently described speciesT. krajdenii had a sequence identical to that ofT. mentagrophytes isolates related to the teleomorphArthroderma vanbreuseghemii .

rRNA Gene Internal Transcribed Spacer 1 and 2 Sequences of Asexual, Anthropophilic Dermatophytes Related to Trichophyton rubrum