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In the allosteric aspartate transcarbamylase (ATCase) from the hyperthermophilic eubacteriumThermotoga maritima , the catalytic and regulatory functions, which in class B ATCases are carried out by specialized polypeptides, are combined on a single type of polypeptide assembled in trimers. The ATCases fromT. maritima andTreponema denticola present intriguing similarities, suggesting horizontal gene transfer.

journal of bacteriology

Aspartate Transcarbamylase from the Hyperthermophilic Eubacterium <i>Thermotoga maritima</i> : Fused Catalytic and Regulatory Polypeptides Form an Allosteric Enzyme

Aspartate Transcarbamylase from the Hyperthermophilic Eubacterium Thermotoga maritima : Fused Catalytic and Regulatory Polypeptides Form an Allosteric Enzyme