A third unlinked gene controlling the pyruvate dehydrogenase complex in Aspergillus nidulans | Zendy

C.J. Bos | Zendy; Marijke Slakhorst | Zendy; Jaap Visser | Zendy; Clive F. Roberts | Zendy

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A third unlinked gene controlling the pyruvate dehydrogenase complex in Aspergillus nidulans

Author(s) -

C.J. Bos,

Marijke Slakhorst,

Jaap Visser,

Clive F. Roberts

Publication year - 1981

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.148.2.594-599.1981

Subject(s) - biology , pyruvate dehydrogenase complex , aspergillus nidulans , mutant , gene , biochemistry , enzyme , dehydrogenase , genetics

Pyruvate dehydrogenase complex mutants of Aspergillus nidulans were obtained by ultraviolet treatment and enrichment procedures. Among 160 glycolytic mutants, 86 pyruvate dehydrogenase complex mutants (including some temperature-sensitive mutants) were found. In addition to genes pdhA and pdhB, which are described in previous studies, a third gene, pdhC, controlling the function of the enzyme complex, was identified. The three genes were not linked and were mapped in the following linkage groups: pdhA in group I, pdhB in group V, and pdhC in group VIII, where it was the first marker on the left arm.

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