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Escherichia coli K-12 strains that carry mutations in one or more genes coding for proteins involved in repair of deoxyribonucleic acid lesions are more sensitive to the antibiotic nitrofurantoin than are the nonmutant parent strains.

Effect of Mutations in Deoxyribonucleic Acid Repair Pathways on the Sensitivity of Escherichia coli K-12 Strains to Nitrofurantoin