English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

TheEscherichia coli suppressor mutation,supT , has been shown to cause a C → U substitution in the middle position of the tRNAGGG Gly anticodon. This is the same tRNA species that is altered by theglyUsu AGA mutation studied previously. This finding indicates that thesupT mutant tRNA reads the glutamic acid codon, GAG. ThesupT suppressor has also been converted to a new suppressor, calledglyUsu GAA , which will suppress the GAA mutation,trpA46 . The in vivo suppression efficiencies of each of these three missense suppressors has been measured and are as follows:glyUsu AGA , 3.6%;supT , 1.6%; andglyUsu GAA , 0.4%. Mistranslation by these mutant glycine tRNA species has no adverse affects on cell growth since cultures possessing the suppressors grow as fast as cells without. ThesupT tRNA species can be observed as a peak in the profile of glycyl-tRNA fractionated on a RPC-5 chromatographic column, indicating that the mutant tRNA can be aminoacylated with reasonable efficiency. This finding contrasts with previous findings concerning theglyUsu AGA mutant tRNA which is not significantly aminoacylated under the same conditions.

Three Different Missense Suppressor Mutations Affecting the tRNA GGG Gly Species of Escherichia coli

Three Different Missense Suppressor Mutations Affecting the tRNA _GGG ^Gly Species of Escherichia coli