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Levels of deoxyribonuclease and ribonuclease activities in the supernatant (soluble plus ribosomes) fraction ofMycoplasma gallisepticum were assayed and found to be a function of strain, nutrient, and culture age. In yeast hydrolysate-enriched broth, maximal nuclease activities occurred during exponential growth.

Nuclease Activities of Mycoplasma gallisepticum as a Function of Culture Age in Different Media