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The results show that CD4 T cells specific for a recombinant antigen expressed inSalmonella typhimurium proliferate normally in mice that express the susceptible form of theIty gene at early times after infection but do not retain the capacity to produce gamma interferon later in the infection.

infection and immunity

Clonal Expansion of Antigen-Specific CD4 T Cells following Infection with Salmonella typhimurium Is Similar in Susceptible ( Ity s ) and Resistant ( Ity r ) BALB/c Mice